Cocktail culture began in the home and broke down norms around who socialized with whom, gender-wise, and I certainly know people who assume all cocktails are sweet and sugary (and therefore feminine), or that any drink with more than two ingredients is a "girly" drink. Neither of those things are true, of course, as anyone with an alcoholic grandfather or an even passing familiarity with James Bond can attest. And, I mean, Ernest Hemingway drank mojitos and daiquiris (albeit not the frozen, flavored concoction usually called a daiquiri these days).
Also, tiki drinks – usually mixed on rum, and full of sweet ingredients that will charm the teeth straight out of your mouth! These are drinks people like Howard Hughes used to love in the postwar period, and that have become popular among lovers of craft cocktails in the last few years. Tiki drinks, as far as I can tell, are largely detached from "girly drink" stigma, possibly because most of the classics are so full of booze that their moribund names (the Zombie, the Corpse Reviver, the Suffering Bastard) should serve as a warning, a kind of macho throwdown: "Just because I am full of fruity, tropical flavors and rum does not mean I cannot kill you dead, sir!"
Of course, the fact that a fictitious jerky, misogynistic spy likes something or an actual jerky, misogynistic writer liked something does not automatically make that thing good. Or bad. (Let's not even mention Don Draper and his old fashioneds.) Nor should we assume any correlation between urine-hoarding and knowledgeability about cocktails. And while I'm still snobbish enough to make faces when I walk into a bar and the drink menu includes things like appletinis (or, really, anything that's just vodka and flavored syrup in a martini glass), it stands to reason that not every drink pegged as a "girl drink" tastes like a blue Slush Puppy.